Ask the Dermatologist: Why do Some Zits hurt more than Others? Pimples that honestly harm are extra than 'acne'," says Dr. Ostad. "they may be inflamed cysts — large acne or boils. They harm due to the fact they're more inflamed and the inflammation may be on top of or close to a minor nerve ending which causes ache. And unfortunately, the extra irritation the extra ache there is." I need a treatment stat ? "The pleasant way to reduce pain is a warm compress and to apply over-the-counter benzoyl peroxide two times every day," he advises. "over the counter hydro-cortisone 1% can also help reduce infection." To lessen the dimensions of a pimple avoid stress and for goodness sake, cease selecting at it. How to Decrease The ache The excellent way to lower the ache of a pimple is similar to if you have an infected ‘egg’ to your head after hitting it – – – ice it! keep ice to the region for 5 mins on, 5mins off, as frequentl